Automated control systems comprised of electrochemical and/or optical pH and dissolved oxygen sensors for aqueous media, temperature sensors for aqueous media, pressure sensors for single-use containers , mass flow control valves for regulating gas concentration and/or peristaltic and/or diaphragm pumps for regulating liquid flow in aqueous bioprocess media, computer hardware for controlling communication between bioprocess monitoring instrumentation, actuators and diagnostic software; and controller software for monitoring and controlling equipment and processes for bioreactors, mixers, filtration skids and chromatography or liquid separation systems

'actuat':59 'and/or':7,37,39 'aqueous':15,20,47 'autom':1 'bioprocess':48,56 'bioreactor':74 'chromatographi':79 'communic':54 'compris':4 'comput':50 'concentr':36 'contain':28 'control':2,31,53,64,69 'diagnost':61 'diaphragm':40 'dissolv':11 'electrochem':6 'equip':70 'filtrat':76 'flow':30,45 'gas':35 'hardwar':51 'instrument':58 'liquid':44,81 'mass':29 'media':16,21,49 'mixer':75 'monitor':57,67 'optic':8 'oxygen':12 'peristalt':38 'ph':9 'pressur':22 'process':72 'pump':41 'regul':34,43 'sensor':13,18,23 'separ':82 'singl':26 'single-us':25 'skid':77 'softwar':62,65 'system':3,83 'temperatur':17 'use':27 'valv':32

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