Cell directed therapy based on the use of alpha particle emitting isotopes, in particular, but not limited to Actinium-225 and Bismuth-213, labeled onto selected cell targeting agents, in particular, but not limited to peptides and mono clonal antibodies, or derivatives thereof This therapeutic concept refers to the treatment of cellular diseases, including cancer, auto-immune diseases (such as Rheumatoid Arthritis and Lupus Erythematosus),and AIDS

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