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SCIENTIFIC RESEARCH, NAMELY, RESEARCH AND DEVELOPMENT OF A FUNCTIONAL GENOMICS LABORATORY TECHNIQUE TO RAPIDLY GUIDE TARGET VALIDATION; SCIENTIFIC RESEARCH, NAMELY, RESEARCH AND DEVELOPMENT OF THE USE OF MESSENGER RNA INHIBITORS OR ANTI SENSE OLIGONUCLEOTIDES TO INHIBIT OR MODIFY GENE EXPRESSION OF TARGET ENZYMES, GENES OR MESSENGER RNA OF THE TARGET OR GENE AND THE DETERMINATION OF THE EFFECT OF THIS INHIBITION OR MODIFICATION ON NORMAL OR DISEASED CELLS; MEDICAL TESTING, NAMELY, CONDUCTING IN-VITRO LABORATORY ASSAYS OR LABORATORY TESTS IN LAB DISHES OR HIGH THROUGHPUT SCREENING FORMATS TO INHIBIT OR MODIFY THE GENE EXPRESSION AND PROTEIN OR ENZYMES OF THE TARGET; LABORATORY TESTING, NAMELY, ANALYZING GENE INHIBITION OR MODIFICATION IN LABORATORY TESTS REGARDING THE ROLE OF THE ENZYME, PROTEIN OR GENE IN DISEASE THROUGH THE USE OF SPECIFIC CELLULAR AND FUNCTIONAL ASSAYS OR LABORATORY TESTS; MEDICAL SERVICES, NAMELY, USING INFORMATION REGARDING THE RESULTS OF GENE INHIBITION OR MODIFICATION TO INHIBIT OR MODIFY AN ENZYME, GENE OR PROTEIN TARGET OR MULTIPLE ISOFORMS OF AN ENZYME, GENE OR PROTEIN TARGET; MEDICAL SERVICES, NAMELY, INHIBITING OR MODIFYING MESSENGER RNA OF A GENE, ENZYME OR PROTEIN TARGET AND UTILIZING OR PROVIDING RESULTING INFORMATION REGARDING SUCH INHIBITION OR MODIFICATION ON NORMAL AND DISEASED CELLS