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Scientific and industrial research in the field of biochemistry; services of a biochemical laboratory, in particular synthesis of recombinant polypeptides and proteins for production of chemical substances for industrial use, namely, propanedioic acid, ethyl malonate, mono-methyl malonate, mono-ethyl malonate, mono-ethyl malonate, mono-propyl malonate, mono-butyl malonate, mono-tert-butyl malonate, and the like, di-alkyl malonate esters, namely, dimethyl malonate, diethyl malonate, dipropyl malonate, dibutyl malonate, and the like, Meldrum's acid, dialkyl malonate, e-caprolactam, d-valerolactam, dialkylated 1,3-dicarbonyl compounds, namely, diethyl 2,2-dimethylmalonate, diethyl 2,2-diethylmalonate, diethyl 2,2-dipropylmalonate, diethyl 2,2-dibutylmalonate, dimethyl 2,2-dimethylmalonate, dimethyl 2,2-diethylmalonate, dimethyl 2,2-dipropylmalonate, and dimethyl 2,2-dibutylmalonate, lactic acid, pyruvic acid, hydroxypropionic acid, formate, succinic acid, 1,3-propanediol, and 2,3-butanediol, 1,4-butanediol