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Active chemical ingredients for use in the manufacture of pharmaceuticals for treating physical and mental disorders in the nature of epilepsy, convulsions, seizures, nerve damage, pain, chronic pain, inflammation, acne, psoriasis, heart disease, hypertension, coronary artery disease (atherosclerosis), muscle disorders, muscle spasms, bone deficiency, Parkinson disease, Crohn disease, multiple sclerosis, immune disorders, fungal infections, bacterial infections, nausea, vomiting, appetite loss, small intestine disorders, diabetes, high blood sugar, cancer and side effects from the treatment of cancer, Huntington disease, symptoms of withdrawal, temporomandibular disorders, insomnia, trouble sleeping, anxiety, depression, schizophrenia, and bipolar disorder